EXPLORING THE UTILITY OF RECOMBINANT SNAKE VENOM SERINE PROTEASE TOXINS AS IMMUNOGENS FOR GENERATING EXPERIMENTAL SNAKEBITE ANTIVENOMS

Exploring the Utility of Recombinant Snake Venom Serine Protease Toxins as Immunogens for Generating Experimental Snakebite Antivenoms

Snakebite is a neglected tropical disease that causes high rates of global mortality and morbidity.Although snakebite can cause a variety of pathologies in victims, haemotoxic effects are particularly common and are typically characterised by haemorrhage and/or venom-induced consumption coagulopathy.Despite First Aid Kits polyclonal antibody-based

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Collective order and group structure of shoaling fish subject to differing risk-level treatments with a sympatric predator

It is imperative for individuals to First Aid Kits exhibit flexible behaviour according to ecological context, such as available resources or predation threat.Manipulative studies on responses to threat often focus on behaviour in the presence of a single indicator for the potential of predation, whereas in the wild perception of threat will probab

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Anti-cytotoxic T lymphocyte antigen-4 antibodies in melanoma

Giulio Tosti, Emilia Cocorocchio, Elisabetta PennacchioliDivisione Melanomi e Sarcomi, Istituto Europeo di Oncologia, Milano, ItalyAbstract: Approaches aimed at enhancement of the tumor specific response have provided proof for the rationale of immunotherapy in cancer, both in animal models and in humans.Ipilimumab, an anti-cytotoxic T lymphocyte a

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Characterization of MED12, HMGA2, and FH alterations reveals molecular variability in uterine smooth muscle tumors

Abstract Uterine smooth muscle tumors range from benign leiomyomas to malignant leiomyosarcomas.Based on numerous molecular studies, leiomyomas and leiomyosarcomas mostly lack shared mutations and the majority of tumors are believed to develop through distinct mechanisms.To further characterize the molecular variability among uterine smooth muscle

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A Reading of Article 21 of the United Nations Declaration of Human Rights: Political (Dis)engagement in the Context of Brexit

Free, regular, and open elections are sought-after qualities of a liberal democracy.Reading electoral turnout as an indicator of political engagement, though, is a reductive reading and can obscure entrenched levels of political disengagement.This article considers the implications First Aid Kits of Article 21, subsection one, of the United Nations

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